BDBM50335867 3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)-1H-1,2,3-triazol-4-yl)-6-hydroxy-2-para-tolylbenzofuran-5-carboxylic Acid::CHEMBL1650891

SMILES Cc1ccc(cc1)-c1oc2cc(O)c(cc2c1-c1cn(CCCC(=O)Nc2ccc(Cl)c3ccccc23)nn1)C(O)=O

InChI Key InChIKey=SFPAQPMKUYAZGZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50335867   

TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  380nMAssay Description:Inhibition of recombinant LyP assessed as hydrolysis of DiFMUPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  205nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  2.37E+4nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of CD45More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  3.69E+3nMAssay Description:Inhibition of HePTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50335867(3-(1-(4-(4-Chloronaphthalen-1-ylamino)-4-oxobutyl)...)
Affinity DataIC50:  378nMAssay Description:Inhibition of Shp1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed