BDBM50336751 5-[3-Methoxy-4-(4-nitro-3-trifluoromethylphenoxy)benzylidene]-thiazolidine-2,4-dione::CHEMBL1671959

SMILES COc1cc(C=C2SC(O)=NC2=O)ccc1Oc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O

InChI Key InChIKey=ZRKIDFSLYHMIMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336751   

TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50336751(5-[3-Methoxy-4-(4-nitro-3-trifluoromethylphenoxy)b...)
Affinity DataIC50:  280nMAssay Description:Agonist activity at 6his-tagged ERRalpha LBD assessed as recruitment of GST-labeled coactivator Scr2 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50336751(5-[3-Methoxy-4-(4-nitro-3-trifluoromethylphenoxy)b...)
Affinity DataIC50:  5.00E+3nMAssay Description:Antagonist activity at ERRalpha LBD expressed in HEK293 cells assessed as Gal4-SRC2 interaction by two hybrid luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed