BDBM50336885 2-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-1-[4-(5-fluoropyridin-2-yl)phenyl]propan-2-ol::CHEMBL1672351

SMILES CC(C)(C)Cc1cnc([nH]1)C(C)(O)Cc1ccc(cc1)-c1ccc(F)cn1

InChI Key InChIKey=WFOBNYAVMIYRCG-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50336885   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336885(2-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-1-[4-(...)
Affinity DataKi:  5.90E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336885(2-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-1-[4-(...)
Affinity DataIC50:  82nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin (6-14) from human BRS-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBombesin receptor subtype-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50336885(2-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-1-[4-(...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at human BRS-3 expressed in HEK293AEQ cells assessed as induction of intracellular calcium mobilization by aequorin bioluminescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed