BDBM50336890 (+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylpropan-1-amine::CHEMBL1672374::US10913711, Compound 200::US11555013, Compound 200::US9862679, Compound 200

SMILES O=S(CCNCCCc1ccccc1)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=QCMUGORVKCWDCX-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50336890   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  194nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  194nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quickly frozen. Membranes were prepared b...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  194nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  194nMAssay Description:Dopamine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs) were removed, striatum dissected and quick...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  1.00E+3nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  1.00E+3nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain dissected and rapidly frozen. Membran...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  1.00E+3nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuroepithelial cell-transforming 1(Rat)
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  2.35E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  2.35E+3nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  2.35E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50336890((+/-)-N-(2-(benzhydrylsulfinyl)ethyl)-3-phenylprop...)
Affinity DataKi:  2.35E+3nMAssay Description:Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, frontal cortex dissected and rapidly frozen. M...More data for this Ligand-Target Pair
In DepthDetails US Patent