BDBM50336897 (+/-)-2-(Bis(4-fluorophenyl)methylsulfinyl)acetamide::CHEMBL1672359

SMILES NC(=O)CS(=O)C(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=YEAQNUMCWMRYMU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50336897   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336897((+/-)-2-(Bis(4-fluorophenyl)methylsulfinyl)acetami...)
Affinity DataKi:  2.19E+3nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336897((+/-)-2-(Bis(4-fluorophenyl)methylsulfinyl)acetami...)
Affinity DataKi:  4.09E+3nMAssay Description:Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatal membranes incubated for 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336897((+/-)-2-(Bis(4-fluorophenyl)methylsulfinyl)acetami...)
Affinity DataKi:  4.87E+4nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-Dawley rat midbrain membranes incubated for 60 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
National Institute On Drug Abuse - Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50336897((+/-)-2-(Bis(4-fluorophenyl)methylsulfinyl)acetami...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed