BDBM50337204 4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-cyano-[1,1'-biphenyl]-3-yl)amino)-4-methyl-1-oxopentan-2-yl)amino)-2-(4-cyanobenzamido)-3-oxopropyl)phenyl dihydrogen phosphate::CHEMBL1681825

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)c1ccc(cc1)C#N)C(=O)Nc1cc(cc(c1)-c1ccc(cc1)C#N)C(=O)NCc1ccccc1

InChI Key InChIKey=GJFOCANYFVUXTR-ZAQUEYBZSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337204   

TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50337204(4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-cyano-[1...)
Affinity DataKi:  3.60E+4nMAssay Description:Displacement of 5-carboxyfluorescein-GpYLPQTV-NH2 from mouse recombinant His-tagged STAT3-SH2 domain expressed in Escherichia coli BL21 (DE3) by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50337204(4-((S)-3-(((S)-1-((5-(Benzylcarbamoyl)-4'-cyano-[1...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed