BDBM50338359 CHEMBL1682897::rac-1-Chloro-6-[1-hydroxy-1-(1H-imidazol-4-yl)-2-methylpropyl]-N-methyl-2-naphthamide

SMILES CNC(=O)c1ccc2cc(ccc2c1Cl)C(O)(C(C)C)c1cnc[nH]1

InChI Key InChIKey=APPKRPXUNINZJS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338359   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338359(CHEMBL1682897 | rac-1-Chloro-6-[1-hydroxy-1-(1H-im...)
Affinity DataIC50:  91nMAssay Description:Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338359(CHEMBL1682897 | rac-1-Chloro-6-[1-hydroxy-1-(1H-im...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338359(CHEMBL1682897 | rac-1-Chloro-6-[1-hydroxy-1-(1H-im...)
Affinity DataIC50:  200nMAssay Description:Inhibition of 17,20 lyase activity in humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed