BDBM50339379 (+/-)-3-(4-Chlorophenyl)-2-((R)-1-(4-chlorophenyl)ethyl)-3-((1-(hydroxymethyl)cyclopropyl)methoxy)isoindolin-1-one::CHEMBL1688284

SMILES C[C@@H](N1C(=O)c2ccccc2C1(OCC1(CO)CC1)c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=IYUMLCRMDKLSQE-XZATXCMXSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339379   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL

LigandBDBM50339379((+/-)-3-(4-Chlorophenyl)-2-((R)-1-(4-chlorophenyl)...)Copy SMILESCopy InChI

Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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