BDBM50339414 2-(4-bromobenzyl)-3-(4-chlorophenyl)-3-hydroxyisoindolin-1-one::CHEMBL1688140

SMILES OC1(N(Cc2ccc(Br)cc2)C(=O)c2ccccc12)c1ccc(Cl)cc1

InChI Key InChIKey=QAMBGJZBFAREOH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339414   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL

LigandBDBM50339414(2-(4-bromobenzyl)-3-(4-chlorophenyl)-3-hydroxyisoi...)Copy SMILESCopy InChI

Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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