BDBM50339424 CHEMBL1688159::Methyl 4-((1-(4-chlorophenyl)-1-hydroxy-3-oxoisoindolin-2-yl)methyl)benzoate

SMILES COC(=O)c1ccc(CN2C(=O)c3ccccc3C2(O)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=YQGYZGTXNKOHHM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339424   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339424(CHEMBL1688159 | Methyl 4-((1-(4-chlorophenyl)-1-hy...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed