BDBM50340457 CHEMBL1761858::Exo-((1R,5S)-3-(1H-pyrazol-3-yl)-8-azabicyclo[3.2.1]octan-8-yl)(3,4-dihydroquinolin-1(2H)-yl)methanone

SMILES O=C(N1[C@H]2CC[C@@H]1C[C@H](C2)c1ccn[nH]1)N1CCCc2ccccc12

InChI Key InChIKey=XBWSJCDFRIBITA-OSYLJGHBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340457   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340457(CHEMBL1761858 | Exo-((1R,5S)-3-(1H-pyrazol-3-yl)-8...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed