BDBM50340457 CHEMBL1761858::Exo-((1R,5S)-3-(1H-pyrazol-3-yl)-8-azabicyclo[3.2.1]octan-8-yl)(3,4-dihydroquinolin-1(2H)-yl)methanone
SMILES O=C(N1[C@H]2CC[C@@H]1C[C@H](C2)c1ccn[nH]1)N1CCCc2ccccc12
InChI Key InChIKey=XBWSJCDFRIBITA-OSYLJGHBSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50340457
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair