BDBM50340501 1-((2-(ethylamino)pyridin-4-yl)methyl)-5,5-dimethyl-3-(4-(trifluoromethylthio)phenyl)imidazolidine-2,4-dione::CHEMBL1762177

SMILES CCNc1cc(CN2C(=O)N(C(=O)C2(C)C)c2ccc(SC(F)(F)F)cc2)ccn1

InChI Key InChIKey=VGMFSXIEWAKOFX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340501   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50340501(1-((2-(ethylamino)pyridin-4-yl)methyl)-5,5-dimethy...)
Affinity DataIC50:  154nMAssay Description:Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in SF21 cells after 10 mins by time resolved-fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50340501(1-((2-(ethylamino)pyridin-4-yl)methyl)-5,5-dimethy...)
Affinity DataIC50:  47nMAssay Description:Inhibition of autophosphosphorylation of human IGF1R expressed in IGF1-stimulated MCF7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50340501(1-((2-(ethylamino)pyridin-4-yl)methyl)-5,5-dimethy...)
Affinity DataIC50:  154nMAssay Description:Inhibition of IGF-induced autophosphosphorylation of GST-tagged human IGF1R expressed in SF21 cells by time resolved-fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed