BDBM50340651 CHEBI:6039::Isopimaric Acid::acs.jmedchem.1c00409_ST.790

SMILES [H][C@]12CC[C@@](C)(CC1=CC[C@@]1([H])[C@@](C)(CCC[C@]21C)C(O)=O)C=C

InChI Key InChIKey=HDWPMPWOTAUENM-QOCHGBHMSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50340651   

TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50340651(CHEBI:6039 | Isopimaric Acid | acs.jmedchem.1c0040...)
Affinity DataEC50:  2.60E+4nMAssay Description:Transactivation of human Gal4-fused RXRalpha LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50340651(CHEBI:6039 | Isopimaric Acid | acs.jmedchem.1c0040...)
Affinity DataEC50:  3.20E+4nMAssay Description:Transactivation of human Gal4-fused RXRbeta LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University

LigandPNGBDBM50340651(CHEBI:6039 | Isopimaric Acid | acs.jmedchem.1c0040...)
Affinity DataIC50:  2.84E+5nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Michigan State University

LigandPNGBDBM50340651(CHEBI:6039 | Isopimaric Acid | acs.jmedchem.1c0040...)
Affinity DataIC50:  2.84E+5nMAssay Description:Inhibition of SARS coronavirus 3C-like protease after 60 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Swiss Federal Institute Of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50340651(CHEBI:6039 | Isopimaric Acid | acs.jmedchem.1c0040...)
Affinity DataEC50:  3.30E+4nMAssay Description:Transactivation of human Gal4-fused RXRgamma LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed