BDBM50340669 5,7-difluoro-2,2-dimethyl-6-(3-methyl-1H-indol-7-yl)-2,3-dihydroquinolin-4(1H)-one O-benzyl oxime::CHEMBL1762206
SMILES Cc1c[nH]c2c(cccc12)-c1c(F)cc2NC(C)(C)C\C(=N/OCc3ccccc3)c2c1F
InChI Key InChIKey=AWWXSWMNIGJPHA-WEMUVCOSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50340669
Affinity DataKi: 5.80nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Transrepression activity at glucocorticoid receptor in human HepG2 cells assessed as inhibition of TNFalpha/IL1beta-stimulated NFkappaB-dependent E-s...More data for this Ligand-Target Pair