BDBM503409 6-Amino-2-[(4-amino-cyclohexyl)- methyl-amino]-5-(2,3-dichloro- phenyl)-pyrimidine-4-carboxylic acid amide::US11033547, Compound 112::US11696916, Compound 112
SMILES CN([C@H]1CC[C@H](N)CC1)c1nc(N)c(-c2cccc(Cl)c2Cl)c(n1)C(N)=O
InChI Key InChIKey=CJJBPECAZYUJHQ-MGCOHNPYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503409
Affinity DataIC50: 66nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair