BDBM50341470 9-Isoquinolin-4-yl-1,2,6,7-tetrahydro-5H-pyrido[3,2,1-ij]quinolin-3-one::CHEMBL1765215

SMILES O=C1CCc2cc(cc3CCCN1c23)-c1cncc2ccccc12

InChI Key InChIKey=JQCBIGRJLIUCSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341470   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50341470(9-Isoquinolin-4-yl-1,2,6,7-tetrahydro-5H-pyrido[3,...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79 MZh cells assessed as conversion of [4-14C]-11-deoxycorticosterone substrate by HPTLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50341470(9-Isoquinolin-4-yl-1,2,6,7-tetrahydro-5H-pyrido[3,...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79 MZh cells assessed as conversion of [4-14C]-11-deoxycorticosterone substrate by HPTLC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed