BDBM503415 (5M)-6-amino-2-[(1S)-1-amino-1,3- dihydrospiro[indene-2,4'-piperidin]-1'- yl]-5-(2,3-dichlorophenyl)pyrimidine-4- carboxamide::US11033547, Compound 118
SMILES N[C@@H]1c2ccccc2CC11CCN(CC1)c1nc(N)c(C2=CC=C[C@H](Cl)[C@@H]2Cl)c(n1)C(N)=O
InChI Key InChIKey=LHONEWDOUCEQTH-ILZDJORESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 503415
Affinity DataIC50: 41nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair