BDBM50341765 (S)-2-Phenyl-5-trifluoromethyloxazole-4-carboxylic Acid-[2-(3-Hydroxypyrrolidin-1-yl)pyrimidin-5-yl]amide::CHEMBL1766883

SMILES O[C@H]1CCN(C1)c1ncc(NC(=O)c2nc(oc2C(F)(F)F)-c2ccccc2)cn1

InChI Key InChIKey=JOAQPUGHMNETNS-ZDUSSCGKSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341765   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341765((S)-2-Phenyl-5-trifluoromethyloxazole-4-carboxylic...)
Affinity DataIC50:  237nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected insect cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50341765((S)-2-Phenyl-5-trifluoromethyloxazole-4-carboxylic...)
Affinity DataEC50:  5.66E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHO-K1 cells after 1 hr using palmitoyl-1-14C-coenzyme A by phospholipid flashplate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed