BDBM50342279 (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxy-benzofuran-3-yl)methanone::CHEMBL1767079::US9725430, Compound 1g::US9962362, Compound 1g
SMILES CCc1oc2cc(O)ccc2c1C(=O)c1cc(Br)c(O)c(Br)c1
InChI Key InChIKey=FEXBXMFVRKZOOZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50342279
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus
Curated by ChEMBL
University Of Colorado Anschutz Medical Campus
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...More data for this Ligand-Target Pair
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus
Curated by ChEMBL
University Of Colorado Anschutz Medical Campus
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human URAT1 expressed in human MDCK cellsMore data for this Ligand-Target Pair
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus
Curated by ChEMBL
University Of Colorado Anschutz Medical Campus
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of URAT1 (unknown origin) transfected in dog MDCK cells assessed as inhibition of [14C]uric acid uptake by liquid scintillation counting m...More data for this Ligand-Target Pair
TargetEyes absent homolog 3(Homo sapiens (Human))
Cincinnati Childrens Hospital Medical Center
US Patent
Cincinnati Childrens Hospital Medical Center
US Patent
Affinity DataIC50: 2.72E+4nMAssay Description:The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...More data for this Ligand-Target Pair
TargetEyes absent homolog 3(Homo sapiens (Human))
Cincinnati Childrens Hospital Medical Center
US Patent
Cincinnati Childrens Hospital Medical Center
US Patent
Affinity DataIC50: 2.72E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair