BDBM50342287 (3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxybenzofuran-3-yl)methanone::CHEMBL1767107::US9725430, Compound 1h::US9962362, Compound 1h

SMILES CCc1oc2ccc(O)cc2c1C(=O)c1cc(Br)c(O)c(Br)c1

InChI Key InChIKey=QWHPIJVTUFQZOL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342287   

TargetSolute carrier family 22 member 12(Homo sapiens (Human))
University Of Colorado Anschutz Medical Campus

Curated by ChEMBL
LigandPNGBDBM50342287((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...)
Affinity DataIC50:  189nMAssay Description:Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEyes absent homolog 3(Homo sapiens (Human))
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50342287((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...)
Affinity DataIC50:  4.08E+4nMAssay Description:The compounds were then tested using full-length human recombinant, purified EYA3 and pNPP as a substrate. Compounds were dissolved in DMSO and dilut...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEyes absent homolog 3(Homo sapiens (Human))
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50342287((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...)
Affinity DataIC50:  4.08E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In DepthDetails US Patent