BDBM50342562 (E)-4-chloro-3-(2-oxopropylidene)indolin-2-one::CHEMBL1770394

SMILES CC(=O)C=C1C(=O)Nc2cccc(Cl)c12

InChI Key InChIKey=GMPLJVLJHVOIEU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342562   

TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342562((E)-4-chloro-3-(2-oxopropylidene)indolin-2-one | C...)
Affinity DataKi:  700nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342562((E)-4-chloro-3-(2-oxopropylidene)indolin-2-one | C...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed