BDBM50342564 (E)-6-fluoro-3-(2-oxopropylidene)indolin-2-one::CHEMBL1770396

SMILES CC(=O)C=C1C(=O)Nc2cc(F)ccc12

InChI Key InChIKey=DDCYETLSUPMGES-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342564   

TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342564((E)-6-fluoro-3-(2-oxopropylidene)indolin-2-one | C...)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342564((E)-6-fluoro-3-(2-oxopropylidene)indolin-2-one | C...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342564((E)-6-fluoro-3-(2-oxopropylidene)indolin-2-one | C...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed