BDBM50342691 1-(5-chloropyrimidin-2-yl)-1'-(4-(methylsulfonyl)phenyl)-4,4'-bipiperidine::CHEMBL1770161

SMILES CS(=O)(=O)c1ccc(cc1)N1CCC(CC1)C1CCN(CC1)c1ncc(Cl)cn1

InChI Key InChIKey=PYPROMLQJSTKNW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342691   

TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50342691(1-(5-chloropyrimidin-2-yl)-1'-(4-(methylsulfonyl)p...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50342691(1-(5-chloropyrimidin-2-yl)-1'-(4-(methylsulfonyl)p...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed