BDBM50342698 (rac)-cis-4-((2-((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)methyl)cyclopropyl)methoxy)-N-cyclopropyl-2-fluorobenzamide::(rac)-trans-4-((2-((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)methyl)cyclopropyl)methoxy)-N-cyclopropyl-2-fluorobenzamide::CHEMBL1771099

SMILES Fc1cc(OCC2CC2CC2CCN(CC2)c2ncc(Cl)cn2)ccc1C(=O)NC1CC1

InChI Key InChIKey=HGXIXRDSWVTXLX-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342698   

TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50342698((rac)-cis-4-((2-((1-(5-chloropyrimidin-2-yl)piperi...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50342698((rac)-cis-4-((2-((1-(5-chloropyrimidin-2-yl)piperi...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50342698((rac)-cis-4-((2-((1-(5-chloropyrimidin-2-yl)piperi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50342698((rac)-cis-4-((2-((1-(5-chloropyrimidin-2-yl)piperi...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50342698((rac)-cis-4-((2-((1-(5-chloropyrimidin-2-yl)piperi...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50342698((rac)-cis-4-((2-((1-(5-chloropyrimidin-2-yl)piperi...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed