BDBM50343052 CHEMBL1770700::N-hydroxy-4-(4-(3-(4-methoxybenzamido)propoxy)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide

SMILES COc1ccc(cc1)C(=O)NCCCOc1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO

InChI Key InChIKey=MASDJPGVHCTFLM-UHFFFAOYSA-N

Data  7 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50343052   

TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi:  550nMAssay Description:Inhibition of human MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi:  900nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi:  900nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataIC50:  550nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343052(CHEMBL1770700 | N-hydroxy-4-(4-(3-(4-methoxybenzam...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed