BDBM50343258 4-((4,4-bis(3-methylthiophen-2-yl)but-3-enyl)(methyl)amino)-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-ol::CHEMBL1773934
SMILES CN(CCC=C(c1sccc1C)c1sccc1C)C1CCCc2o[nH]c(=O)c12
InChI Key InChIKey=CUESOMOCKVRNIW-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50343258
TargetSodium- and chloride-dependent GABA transporter 3(Mus musculus)
Ludwig-Maximilians-University Munich
Curated by ChEMBL
Ludwig-Maximilians-University Munich
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of mouse GAT3-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mus musculus)
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]GABA uptake at GAT2 in mouse astrocytes after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mus musculus)
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT2 expressed in HEK293 cells after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Mus musculus)
Ludwig-Maximilians-University Munich
Curated by ChEMBL
Ludwig-Maximilians-University Munich
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of mouse GAT1-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent betaine transporter(Mus musculus)
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]GABA uptake at GAT2 in mouse neurons after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 3(Mus musculus)
Ludwig-Maximilians-University Munich
Curated by ChEMBL
Ludwig-Maximilians-University Munich
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT4 expressed in HEK293 cells after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT3 expressed in HEK293 cells after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Mus musculus)
Ludwig-Maximilians-University Munich
Curated by ChEMBL
Ludwig-Maximilians-University Munich
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of [3H]GABA uptake at mouse GAT1 expressed in HEK293 cells after 3 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Mus musculus)
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of mouse GAT2-mediated [3H]GABA uptake expressed in human HEK cellsMore data for this Ligand-Target Pair