BDBM50343262 7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-1,6-naphthyridin-2(1H)-one::CHEMBL1774065

SMILES Clc1cccc(N2CCN(CCCCOc3cc4[nH]c(=O)ccc4cn3)CC2)c1Cl

InChI Key InChIKey=IXCOCXDWNZNCFL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343262   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343262(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343262(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343262(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)...)
Affinity DataKi:  40.7nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed