BDBM50343295 2-((4-(2-Methoxy-phenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo[d]imidazole::CHEMBL1774101

SMILES COc1ccccc1C1CCN(Cc2nc3ccccc3n2C)CC1

InChI Key InChIKey=MJDLYRJRCRLNGE-UHFFFAOYSA-N

Data  1 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50343295   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343295(2-((4-(2-Methoxy-phenyl)piperidin-1-yl)methyl)-1-m...)
Affinity DataKi:  426nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50343295(2-((4-(2-Methoxy-phenyl)piperidin-1-yl)methyl)-1-m...)
Affinity DataEC50:  870nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343295(2-((4-(2-Methoxy-phenyl)piperidin-1-yl)methyl)-1-m...)
Affinity DataEC50:  951nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of quinpirole-induced effectMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50343295(2-((4-(2-Methoxy-phenyl)piperidin-1-yl)methyl)-1-m...)
Affinity DataEC50:  87nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed