BDBM50343299 2-((4-(2-Fluorophenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo-[d]imidazole::2-((4-(2-fluorophenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo[d]imidazole::CHEMBL607689
SMILES Cn1c(CN2CCC(CC2)c2ccccc2F)nc2ccccc12
InChI Key InChIKey=AMADNKXMEDYTCS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50343299
Affinity DataKi: 39.8nMAssay Description:Antagonist activity at human D2 receptor expressed in CHO cells co-expressing G0 by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpus striatum by beta plate scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Antagonist activity at human D3 receptor expressed in CHO cells co-expressing G0 by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.58E+4nMAssay Description:Agonist activity at mGluR5More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Positive allosteric modulation of human mGlu2 receptor stably expressed in human Chem-1 cells assessed as potentiation of glutamate-induced intracell...More data for this Ligand-Target Pair
Affinity DataEC50: >1.58E+4nMAssay Description:Positive modulation of mGluR5More data for this Ligand-Target Pair
Affinity DataEC50: 126nMAssay Description:Positive modulation of human mGluR2 expressed in CHO cells co-expressing Ga16 G-protein assessed as glutamate-induced response by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.98E+3nMAssay Description:Agonist activity at human mGluR2 expressed in CHO cells co-expressing Ga16 G-protein assessed as glutamate-induced response by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.58E+4nMAssay Description:Antagonist activity at mGluR1More data for this Ligand-Target Pair
Affinity DataEC50: >1.58E+4nMAssay Description:Agonist activity at mGluR1More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...More data for this Ligand-Target Pair
Affinity DataEC50: >1.58E+4nMAssay Description:Antagonist activity at mGluR5More data for this Ligand-Target Pair