BDBM50343315 CHEMBL1774223::trans-1-((1-Methyl-1H-imidazo[4,5-b]pyridin-2-yl)methyl)-4-(4-(trifluoromethyl)phenyl)piperidin-3-ol

SMILES Cn1c(CN2CCC(C(O)C2)c2ccc(cc2)C(F)(F)F)nc2ncccc12

InChI Key InChIKey=GGANYXPSWRBDMF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343315   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343315(CHEMBL1774223 | trans-1-((1-Methyl-1H-imidazo[4,5-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed