BDBM50343322 CHEMBL1774230::cis-2-(((3S,4S)-4-(4-chloro-2-fluorophenyl)-3-methylpiperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine

SMILES C[C@@H]1CN(Cc2nc3ncccc3n2C)CC[C@@H]1c1ccc(Cl)cc1F

InChI Key InChIKey=HUDWYYYFRVUKIA-HIFRSBDPSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343322   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343322(CHEMBL1774230 | cis-2-(((3S,4S)-4-(4-chloro-2-fluo...)
Affinity DataEC50: >1.81E+3nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed