BDBM50343328 CHEMBL1774236::cis-2-(((3S,4S)-4-(2-fluoro-4-(trifluoromethoxy)phenyl)-3-methylpiperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine

SMILES C[C@@H]1CN(Cc2nc3ncccc3n2C)CC[C@@H]1c1ccc(OC(F)(F)F)cc1F

InChI Key InChIKey=CQTZXNPIJZSXKK-HIFRSBDPSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343328   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50343328(CHEMBL1774236 | cis-2-(((3S,4S)-4-(2-fluoro-4-(tri...)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulator activity at human mGlu2 receptor expressed in rat Chem-1 cells assessed as cytosolic Ca2+ ion concentration measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50343328(CHEMBL1774236 | cis-2-(((3S,4S)-4-(2-fluoro-4-(tri...)
Affinity DataEC50:  818nMAssay Description:Positive allosteric modulation of rat mGluR2 expressed in HEK293 cells co-expressing Galpha15 G protein assessed as increase in glutamate-induced int...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed