BDBM50343449 CHEMBL1775171::isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate

SMILES CC(C)OC(=O)N1CCC(CC1)Oc1ncnc2n(ncc12)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=WMCWRFZUFUHFRB-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343449   

TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50343449(CHEMBL1775171 | isopropyl 4-(1-(4-(methylsulfonyl)...)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at human GPR119 by melanophore assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50343449(CHEMBL1775171 | isopropyl 4-(1-(4-(methylsulfonyl)...)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-dependent insulinotropic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50343449(CHEMBL1775171 | isopropyl 4-(1-(4-(methylsulfonyl)...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed