BDBM50343626 (5alpha)-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphinan-3-yl-((-)-14-methoxyl-17-N-cyclobutylmethyl)morphinan-3-yl-decanedioate::CHEMBL1774948

SMILES CO[C@@]12CCCC[C@@]11CCN(CC3CCC3)[C@@H]2Cc2ccc(OC(=O)CCCCCCCCC(=O)Oc3ccc4C[C@H]5N(CC=C)CC[C@@]67[C@@H](Oc3c46)C(=O)CC[C@@]57O)cc12

InChI Key InChIKey=SBPDOXVIBVEBTB-UEIGNXNKSA-N

Data  3 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50343626   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343626((5alpha)-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphi...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]U69563 from human kappa-opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343626((5alpha)-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphi...)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H]DAMGO from human mu-opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343626((5alpha)-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphi...)
Affinity DataKi:  39nMAssay Description:Displacement of [3H]naltrindole from human delta-opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343626((5alpha)-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphi...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human mu-opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343626((5alpha)-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphi...)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human mu-opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343626((5alpha)-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphi...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human kappa-opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343626((5alpha)-17-Allyl-14-hydroxy-6-oxo-4,5-epoxymorphi...)
Affinity DataIC50:  7.70nMAssay Description:Antagonist activity at human kappa-opioid receptor expressed in CHO cells assessed as inhibition of U69593-induced [35S]GTPgammaS binding after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed