BDBM50343931 (2S,6S,9R,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxytetrahydrofuran-2-yloxy)((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)-6-((S)-2-iminohexahydropyrimidin-4-yl)-2-isopropyl-4,7,10-trioxo-9-pentadecyl-3,5,8,11,15-pentaazaheptadecane-1,17-dioic acid::CHEMBL1780219

SMILES CCCCCCCCCCCCCCC[C@@H](NC(=O)[C@@H](NC(=O)N[C@@H](C(C)C)C(O)=O)[C@@H]1CCN=C(N)N1)C(=O)NCCCN[C@@H]([C@H](O[C@@H]1O[C@H](CN)[C@@H](O)[C@H]1O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)C(O)=O

InChI Key InChIKey=JJBWEBWBMNYISO-NUKHGBOJSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50343931   

TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343931((2S,6S,9R,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminometh...)
Affinity DataKi:  698nMAssay Description:Competitive inhibition of Bacillus subtilis MraY using UDP-MurNAc-pentapeptide as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343931((2S,6S,9R,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminometh...)
Affinity DataKi:  698nMAssay Description:Noncompetitive inhibition of Bacillus subtilis MraY using radiolabeled UDP-GlcNAc as substrate after 30 mins by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343931((2S,6S,9R,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminometh...)
Affinity DataIC50:  740nMAssay Description:Inhibition of Bacillus subtilis MraY using radiolabeled UDP-MurNAc-[14C]pentapeptide as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospho-N-acetylmuramoyl-pentapeptide-transferase(Bacillus subtilis)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343931((2S,6S,9R,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminometh...)
Affinity DataIC50:  740nMAssay Description:Inhibition of purified Bacillus subtilis MraY assessed as incorporation of MurNAc-[14C]pentapeptide into lipid 1 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUndecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase(Thermotoga maritima (strain ATCC 43589 / MSB8 / DS...)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50343931((2S,6S,9R,16S)-16-((S)-((2S,3R,4S,5R)-5-(aminometh...)
Affinity DataIC50:  1.34E+6nMAssay Description:Inhibition of Thermotoga maritima WecA using radiolabeled UDP-[14C]GlcNAc as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed