BDBM50344019 CHEMBL1780085::trans-(3R,5R)-5-(methoxymethyl)-1-((5-methyl-2-phenyloxazol-4-yl)methyl)-N-((tetrahydro-2H-pyran-4-yl)methyl)piperidine-3-carboxamide

SMILES COC[C@@H]1C[C@H](CN(Cc2nc(oc2C)-c2ccccc2)C1)C(=O)NCC1CCOCC1

InChI Key InChIKey=GPQMZENPSPDZPX-IFMALSPDSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344019   

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50344019(CHEMBL1780085 | trans-(3R,5R)-5-(methoxymethyl)-1-...)Copy SMILESCopy InChI

Affinity DataIC50:  1.96nMAssay Description:Inhibition of PDE8BMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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