BDBM50344398 6-cyclopentyl-2-(m-tolylethynyl)-7,8-dihydro-1,6-naphthyridin-5(6H)-one::CHEMBL1779871
SMILES Cc1cccc(c1)C#Cc1ccc2C(=O)N(CCc2n1)C1CCCC1
InChI Key InChIKey=CJPLQFUECHKONH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50344398
Affinity DataKi: 670nMAssay Description:Displacement of [3H]-MPEP from human mGluR5 expressed in HEK293 cells after 2 hrsMore data for this Ligand-Target Pair
Affinity DataEC50: 7.5nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in HEK293 cells assessed as increase of L-glutamate-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair