BDBM50344430 CHEMBL1779994::cis-N-Benzyl-3-methoxy-3,4-dihydrospiro-[[2]benzopyran-1,1'-cyclohexan]-4'-amine

SMILES COC1Cc2ccccc2[C@]2(CC[C@@H](CC2)NCc2ccccc2)O1

InChI Key InChIKey=BITTYRNNBNMMOO-NDVHGFDXSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344430   

TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50344430(CHEMBL1779994 | cis-N-Benzyl-3-methoxy-3,4-dihydro...)
Affinity DataKi:  158nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain by scintillation analyzerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50344430(CHEMBL1779994 | cis-N-Benzyl-3-methoxy-3,4-dihydro...)
Affinity DataKi:  158nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50344430(CHEMBL1779994 | cis-N-Benzyl-3-methoxy-3,4-dihydro...)
Affinity DataKi:  227nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in human RT4 cell membranes incubated for 120 mins in the presence of sigma1 receptor l...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed