BDBM50344474 CHEMBL1780171::cis-4-(4-(2,4-dihydroindeno[1,2-c]pyrazol-6-yl)-3-(pyridin-4-yl)-1H-pyrazol-1-yl)cyclohexanamine

SMILES N[C@H]1CC[C@H](CC1)n1cc(c(n1)-c1ccncc1)-c1ccc-2c(Cc3c[nH]nc-23)c1

InChI Key InChIKey=IITDRWYWCOFDCY-BGYRXZFFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344474   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50344474(CHEMBL1780171 | cis-4-(4-(2,4-dihydroindeno[1,2-c]...)
Affinity DataIC50:  1.52E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50344474(CHEMBL1780171 | cis-4-(4-(2,4-dihydroindeno[1,2-c]...)
Affinity DataIC50:  22.9nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed