BDBM50344476 CHEMBL1780173::cis-(1R,3S)-3-(4-(2,4-dihydroindeno[1,2-c]pyrazol-6-yl)-3-(pyridin-4-yl)-1H-pyrazol-1-yl)cyclohexanol

SMILES O[C@@H]1CCC[C@@H](C1)n1cc(c(n1)-c1ccncc1)-c1ccc-2c(Cc3c[nH]nc-23)c1

InChI Key InChIKey=VKTWVYJAUHKWAJ-VQTJNVASSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344476   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50344476(CHEMBL1780173 | cis-(1R,3S)-3-(4-(2,4-dihydroinden...)
Affinity DataIC50:  607nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50344476(CHEMBL1780173 | cis-(1R,3S)-3-(4-(2,4-dihydroinden...)
Affinity DataIC50:  2nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed