BDBM50344477 6-(1-phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,4-dihydroindeno[1,2-c]pyrazole::CHEMBL1780174

SMILES C1c2c[nH]nc2-c2ccc(cc12)-c1cn(nc1-c1ccncc1)-c1ccccc1

InChI Key InChIKey=WQOHCLXKZOFZAI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344477   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50344477(6-(1-phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,4-...)
Affinity DataIC50:  4.37E+3nMAssay Description:Inhibition of B-Raf-mediated ERK phosphorylation in cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50344477(6-(1-phenyl-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,4-...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed