BDBM50344918 (R)-4-(1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-4-oxo-4,5,7,8-tetrahydro-1H-imidazo[2,1-b]purin-2-yl)benzonitrile::CHEMBL1777943

SMILES CCN1C2=N[C@@H](CN2c2c(nc(-c3ccc(cc3)C#N)n2Cc2ccc(F)c(F)c2)C1=O)C(C)C

InChI Key InChIKey=PHSZXMFHLYCYQZ-NRFANRHFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344918   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344918((R)-4-(1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-...)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed