BDBM50344926 (R)-7-sec-butyl-1-(3,4-difluorobenzyl)-5-ethyl-2-(4-fluorophenyl)-7,8-dihydro-1H-imidazo[2,1-b]purin-4(5H)-one::CHEMBL1777927

SMILES CC[C@H](C)[C@@H]1CN2C(=N1)N(CC)C(=O)c1nc(-c3ccc(F)cc3)n(Cc3ccc(F)c(F)c3)c21

InChI Key InChIKey=WOVLXAYHKIHHPA-BTYIYWSLSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344926   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344926((R)-7-sec-butyl-1-(3,4-difluorobenzyl)-5-ethyl-2-(...)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human P2X7 receptor by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed