BDBM50345219 2-Ethyl-3,3-dimethyl-N-(4-sulfamoylphenyl)butyramide::2-ethyl-3,3-dimethyl-N-(4-sulfamoylphenyl)butanamide::CHEMBL1084856

SMILES CCC(C(=O)Nc1ccc(cc1)S(N)(=O)=O)C(C)(C)C

InChI Key InChIKey=MPEJTVDXBYIUJC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50345219   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50345219(2-Ethyl-3,3-dimethyl-N-(4-sulfamoylphenyl)butyrami...)
Affinity DataKi:  9.60nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50345219(2-Ethyl-3,3-dimethyl-N-(4-sulfamoylphenyl)butyrami...)
Affinity DataKi:  49nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50345219(2-Ethyl-3,3-dimethyl-N-(4-sulfamoylphenyl)butyrami...)
Affinity DataKi:  771nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
The Hebrew University Of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50345219(2-Ethyl-3,3-dimethyl-N-(4-sulfamoylphenyl)butyrami...)
Affinity DataKi:  3.59E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed