BDBM50345420 CHEMBL1784561::N-(4-tert-Butylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

SMILES Cc1cc(Nc2ccc(cc2)C(C)(C)C)n2ncnc2n1

InChI Key InChIKey=YJGFOPGAFBGHRI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345420   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345420(CHEMBL1784561 | N-(4-tert-Butylphenyl)-5-methyl-[1...)
Affinity DataIC50:  78nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345420(CHEMBL1784561 | N-(4-tert-Butylphenyl)-5-methyl-[1...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His6-tagged recombinant human dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as substrate after 10 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed