BDBM50345436 5-Chloro-N-(4-trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::CHEMBL1784713

SMILES FC(F)(F)c1ccc(Nc2cc(Cl)nc3ncnn23)cc1

InChI Key InChIKey=JNIXLHUITKSWMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345436   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345436(5-Chloro-N-(4-trifluoromethyl)phenyl)-[1,2,4]triaz...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of His6-tagged recombinant human dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as substrate after 10 t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50345436(5-Chloro-N-(4-trifluoromethyl)phenyl)-[1,2,4]triaz...)
Affinity DataIC50:  170nMAssay Description:Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogenase expressed in Escherichia coli using L-dihydroorotate as subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed