BDBM50345560 3-(2-(6-methylpyridin-2-yl)ethynyl)-5-nitrobromobenzene::CHEMBL1784606

SMILES Cc1cccc(n1)C#Cc1cc(Br)cc(c1)[N+]([O-])=O

InChI Key InChIKey=GCSNBRLVXIFCQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345560   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Institute For Neurodegenerative Disorders

Curated by ChEMBL
LigandPNGBDBM50345560(3-(2-(6-methylpyridin-2-yl)ethynyl)-5-nitrobromobe...)
Affinity DataIC50:  0.630nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK-293 cells assessed as inhibition of glutamate-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed