BDBM50345657 CHEMBL1784801::rac-3-((1H-imidazol-1-yl)methyl)-1-(3-tert-butyl-4-methoxyphenylsulfonyl)piperidine

SMILES COc1ccc(cc1C(C)(C)C)S(=O)(=O)N1CCCC(Cn2ccnc2)C1

InChI Key InChIKey=CQMOELKVCJWMFD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345657   

TargetAromatase(Homo sapiens (Human))
University Of Chieti 'G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50345657(CHEMBL1784801 | rac-3-((1H-imidazol-1-yl)methyl)-1...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate measured at anoxic conditions by fluorescence analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Chieti 'G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50345657(CHEMBL1784801 | rac-3-((1H-imidazol-1-yl)methyl)-1...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity using 7-methoxy-4-trifluoromethyl coumarin as a substrate by fluorimetr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
University Of Chieti 'G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50345657(CHEMBL1784801 | rac-3-((1H-imidazol-1-yl)methyl)-1...)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of human recombinant aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed