BDBM50345922 3-(3-Fluoro-4-methoxy-phenyl)-9-prop-2-ynylamino-3H-thieno[2,3-d:4,5-d']dipyrimidin-4-one::CHEMBL1784071

SMILES COc1ccc(cc1F)-n1cnc2c(sc3ncnc(NCC#C)c23)c1=O

InChI Key InChIKey=YYVVEJSNAMCCET-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345922   

TargetMetabotropic glutamate receptor 1(RAT)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345922(3-(3-Fluoro-4-methoxy-phenyl)-9-prop-2-ynylamino-3...)
Affinity DataKi:  77nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345922(3-(3-Fluoro-4-methoxy-phenyl)-9-prop-2-ynylamino-3...)
Affinity DataIC50:  212nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345922(3-(3-Fluoro-4-methoxy-phenyl)-9-prop-2-ynylamino-3...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed