BDBM50345936 9-Allylamino-3-(4-fluoro-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one::CHEMBL1783863

SMILES Fc1ccc(cc1)-n1cnc2c(sc3nccc(NCC=C)c23)c1=O

InChI Key InChIKey=FONUUVGMXJQRAK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345936   

TargetMetabotropic glutamate receptor 1(RAT)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345936(9-Allylamino-3-(4-fluoro-phenyl)-3H-pyrido[3',2':4...)
Affinity DataKi:  7.70nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345936(9-Allylamino-3-(4-fluoro-phenyl)-3H-pyrido[3',2':4...)
Affinity DataIC50:  4.40nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345936(9-Allylamino-3-(4-fluoro-phenyl)-3H-pyrido[3',2':4...)
Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed